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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000231454':
IL5 - Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells; Belongs to the IL-5 family.
[a.k.a. R-HSA-912526, IL5-202, XM_011543373.2]
2) '9606.ENSP00000443432':
IDO2 - Indoleamine 2,3-dioxygenase 2; Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. Involved in immune regulation. May not play a significant role in tryptophan-related tumoral resistance.
[a.k.a. IDO2-203, IDO2-204, ENST00000389060]
3) '9606.ENSP00000312134':
PRG2 - Eosinophil granule major basic protein; Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA.
[a.k.a. Q6ICT2, 5553, NP_001230174.1]
4) '9606.ENSP00000430950':
IDO1 - Indoleamine 2,3-dioxygenase 1; Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses. Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells. Acts as a suppressor of anti-tumor immunity. Limits the growth of int [...]
[a.k.a. 5WN8, 6AZV, M86481]
5) '9606.ENSP00000303276':
RNASE2 - Non-secretory ribonuclease; This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities; Belongs to the pancreatic ribonuclease family.
[a.k.a. Non-secretory ribonuclease, RNAS2_HUMAN, RNS2]
6) '9606.ENSP00000336752':
FIP1L1 - Pre-mRNA 3'-end-processing factor FIP1; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex.
[a.k.a. XP_016864158.1, Q6UN15, Q49AU3]
7) '9606.ENSP00000295206':
EN1 - Homeobox protein engrailed-1; Engrailed homeobox 1.
[a.k.a. 2019, ENST00000295206, OTTHUMG00000131401]
8) '9606.NPSR1-AS1':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
9) '9606.ENSP00000302324':
RNASE3 - Eosinophil cationic protein; Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
[a.k.a. OMIM:131398, Eosinophil cationic protein, 4OWZ]
10) '9606.ENSP00000221132':
TNFRSF10A - Tumor necrosis factor receptor superfamily member 10A; Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
[a.k.a. R-HSA-202733, ABK41896.1, HPA050958]