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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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⤓ Mapping
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1) '9606.ENSP00000425493':
CAGE1 - Cancer-associated gene 1 protein; Cancer antigen 1.
[a.k.a. ENSP00000423789, Q8TC20, NP_001164163]
2) '9606.ENSP00000345001':
CRTC1 - CREB-regulated transcription coactivator 1; Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. In the hippocampus, involved [...]
[a.k.a. NP_001091952.1, XM_005259836.3, OTTHUMG00000183115]
3) '9606.ENSP00000354207':
NTRK3 - NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
[a.k.a. ENSP00000485864, AAA75374.1, XM_006720543]
4) '9606.ENSP00000379658':
ETV6 - Transcription factor ETV6; Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation; Belongs to the ETS family.
[a.k.a. 2QB0, ETV6-205, XP_011518909]
5) '9606.ENSP00000269571':
ERBB2 - Receptor tyrosine-protein kinase erbB-2; Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and [...]
[a.k.a. 6BGT, ENST00000582648, ENSP00000269571]
6) '9606.ENSP00000221498':
DKKL1 - Dickkopf-like protein 1; Involved in fertilization by facilitating sperm penetration of the zona pellucida. May promote spermatocyte apoptosis, thereby limiting sperm production. In adults, may reduces testosterone synthesis in Leydig cells. Is not essential either for development or fertility.
[a.k.a. NP_001184230, 27120, UPI0002A4744D]
7) '9606.ENSP00000269305':
TP53 - Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]
[a.k.a. NM_001126113, ENSP00000481638, R-HSA-2559584]
8) '9606.ENSP00000364089':
PAGE3 - PAGE family member 3.
[a.k.a. BC140001, OMIM:300739, XP_016884771.1]
9) '9606.hsa-miR-4695-3p':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000356102':
SLC26A9 - Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Mediates chloride/bicarbonate exchange or chloride-independent bicarbonate extrusion thus assuring bicarbonate secretion. Inhibited by ammonium and thiosulfate. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
[a.k.a. SLC26A9-202, CCDS30989, OTTHUMG00000036001]
