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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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1) '9606.ENSP00000437737':
HTR2A - 5-hydroxytryptamine receptor 2A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2- aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. S [...]
[a.k.a. R-HSA-388396, AAH74848.1, R-HSA-162582]
2) '9606.ENSP00000316244':
HTR1A - 5-hydroxytryptamine receptor 1A; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second [...]
[a.k.a. R-HSA-388396, CAA40962.1, R-HSA-162582]
3) '9606.ENSP00000354859':
DRD2 - D(2) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family.
[a.k.a. ENST00000355319, AF176812, R-HSA-162582]
4) '9606.ENSP00000433769':
CYHR1 - Cysteine and histidine rich 1; Belongs to the CYHR1 family.
[a.k.a. NM_032687, ENST00000533764, AK160381]
5) '9606.ENSP00000270349':
SLC6A3 - Sodium-dependent dopamine transporter; Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
[a.k.a. DAT1, AF306563, AAA35770.1]
6) '9606.ENSP00000276198':
HTR2C - 5-hydroxytryptamine receptor 2C; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,- dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathway [...]
[a.k.a. R-HSA-388396, ENSP00000276198, 5-HT-2C]
7) '9606.RP11-180C1.1':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
8) '9606.ENSP00000496150':
CYP2D6 - Cytochrome P450 2D6; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids, steroids and retinoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the epoxidation of double bonds of polyunsaturated fatty acids (PUFA). Metabolizes endocannabinoid arachidonoylethanolamide (anandamide) to 20-hydroxyeicosatetraenoic acid ethanolamide (20-HETE-EA) and 8,9-, 11,12-, and 14,15-epoxyei [...]
[a.k.a. LOC107987479, LOC107987478, ADF36416.1]
9) '9606.ENSP00000302150':
PRL - Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation; Belongs to the somatotropin/prolactin family.
[a.k.a. CH471087, UPI0001578A5C, NP_000939]
10) '9606.ENSP00000176183':
DRD4 - D(4) dopamine receptor; Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Activated by dopamine, but also by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs. Agonist binding triggers signaling via G proteins that inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).
[a.k.a. 5WIV, R-HSA-388396, DRD4-202]
