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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000329243':
KRT7 - Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7). Belongs to the intermediate filament family.
[a.k.a. 4XIF, CK-7, URS00008BC711]
2) '9606.ENSP00000285071':
FLCN - Folliculin; May be a tumor suppressor. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.
[a.k.a. XP_011522016, FLCN-203, FLCN-204]
3) '9606.ENSP00000371517':
AMACR - Alpha-methylacyl-CoA racemase; Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2- (4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs ; Belongs to the CoA-transferase III family.
[a.k.a. OMIM:604489, ENSG00000242110, NM_203382]
4) '9606.ENSP00000299752':
CDH16 - Cadherin-16; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
[a.k.a. ENSP00000454784, UPI00025A304B, Q6UW93]
5) '9606.ENSP00000292169':
S100A1 - Protein S100-A1; Probably acts as a Ca(2+) signal transducer. In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers a conformational change. This conformational change allows interaction of S1001A with specific target proteins, such as TPR-containing proteins, and the modulation of their activity. Belongs to the S-100 family.
[a.k.a. S-100 protein alpha chain, 2LHL, ENST00000292169.5]
6) '9606.LINC01187':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000288135':
KIT - Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...]
[a.k.a. P10721, 6GQM, 2E9W]
8) '9606.ENSP00000418525':
MME - Neprilysin; Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Belongs to the peptidase M13 family.
[a.k.a. CALLA, MME-213, ENST00000462837.5]
9) '9606.ENSP00000314129':
TFE3 - Transcription factor E3; Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3') (By similarity). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF (By similarity). In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity (By similarity). Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also bin [...]
[a.k.a. Q92757, ENSP00000314129, OTTHUMG00000022690]
10) '9606.ENSP00000271526':
PRCC - Proline-rich protein PRCC; May regulate cell cycle progression through interaction with MAD2L2.
[a.k.a. XP_005245371, PRCC_HUMAN, R-HSA-72203]
