Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
payload active
DISEASES
The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
<- Back
⤓ Mapping
Continue ->
1) '9606.ENSP00000231449':
IL4 - Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages (By similarity). Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4 (By [...]
[a.k.a. BC066277, NX_P05112, BC070123]
2) '9606.ENSP00000351015':
NF1 - Neurofibromin truncated; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.
[a.k.a. J3KSB5, ENSP00000464678, ENST00000468273.1]
3) '9606.ENSP00000443168':
STH - Saitohin.
[a.k.a. uc002ijy.2, NM_001007532.2, AAO03577.1]
4) '9606.SNORD62B':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000231454':
IL5 - Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells; Belongs to the IL-5 family.
[a.k.a. R-HSA-912526, IL5-202, XM_011543373.2]
6) '9606.ENSP00000412237':
IL10 - Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro- inflammatory cytokines i [...]
[a.k.a. uc001hen.2, ENST00000664374, ENSP00000499664]
7) '9606.ENSP00000281038':
NARS2 - Probable asparagine--tRNA ligase, mitochondrial; asparaginyl-tRNA synthetase 2, mitochondrial; Belongs to the class-II aminoacyl-tRNA synthetase family.
[a.k.a. NM_001243251.1, 79731, ENST00000528850.5]
8) '9606.ENSP00000256854':
NARS1 - Asparagine--tRNA ligase, cytoplasmic; Catalyzes the attachment of asparagine to tRNA(Asn) in a two- step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn). In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells.
[a.k.a. R-HSA-379716, CCDS32837.1, ENST00000588661]
9) '9606.ENSP00000011653':
CD4 - T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]
[a.k.a. R-HSA-162587, 3JCC, 4Q6I]
10) '9606.ENSP00000229135':
IFNG - Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.
[a.k.a. ENSG00000111537, IFNG-201, NM_000619]
