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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000391826':
IGF2 - Insulin-like growth factor II Ala-25 Del; The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Ac [...]
[a.k.a. FLJ44734, NM_001127598.2, ENSP00000370796]
2) '9606.ENSP00000223215':
MEST - Mesoderm-specific transcript homolog protein; Mesoderm specific transcript; Belongs to the AB hydrolase superfamily.
[a.k.a. ENST00000475188, ENSP00000401657, XP_024302533]
3) '9606.ENSP00000413720':
CDKN1C - Cyclin-dependent kinase inhibitor 1C; Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life; Belongs to the CDI family.
[a.k.a. ENST00000250707, ENSP00000370101, R-HSA-69278]
4) '9606.KCNQ1OT1':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000493728':
GRB10 - Growth factor receptor-bound protein 10; Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin [...]
[a.k.a. XP_011513625, XP_016867529.1, ENSP00000381790]
6) '9606.ENSP00000353734':
PLAGL1 - Zinc finger protein PLAGL1; Acts as a transcriptional activator. Involved in the transcriptional regulation of type 1 receptor for pituitary adenylate cyclase-activating polypeptide.
[a.k.a. NP_001304090.1, EF100445, OMIM:603044]
7) '9606.ENSP00000494831':
SNRPN - Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events.
[a.k.a. OMIM:182279, Tissue-specific-splicing protein, ENST00000444203]
8) '9606.ENSP00000418259':
ZFP57 - Zinc finger protein 57 homolog; Transcription regulator required to maintain maternal and paternal gene imprinting, a process by which gene expression is restricted in a parent of origin-specific manner by epigenetic modification of genomic DNA and chromatin, including DNA methylation. Acts by controlling DNA methylation during the earliest multicellular stages of development at multiple imprinting control regions (ICRs). Acts together with ZNF445, but ZNF445 seems to be the major factor in human early embryonic imprinting maintenance. In contrast, in mice, ZFP57 plays the predominant [...]
[a.k.a. B2RXJ7, CCDS43436.2, BX120002]
9) '9606.ENSP00000206765':
TGM1 - Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation ; Belongs to the transglutaminase superfamily. Transglutaminase family.
[a.k.a. ENST00000559669, KTG, ENST00000560478.1]
10) '9606.ENSP00000494538':
CTCF - Transcriptional repressor CTCF; Chromatin binding factor that binds to DNA sequence specific sites. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Acts as transcriptional repressor binding to promoters of vertebrate MYC gene and BAG1 gene. Also binds to the PLK and PIM1 promoters. Acts as a transcriptional activator of APP. Regulates APOA1/C3/A4/A5 gene cluster and controls MHC class II gene expression. Plays an essential role in oocyte and preimplantation embryo development by ac [...]
[a.k.a. CTCF-202, R-HSA-5619507, ENSG00000102974]
