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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000430656':
CA1 - Carbonic anhydrase 1; Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.
[a.k.a. Carbonic anhydrase, 1HUG, NP_001729.1]
2) '9606.ENSP00000300900':
CA4 - Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid; Belongs to the alpha-carbonic anhydrase family.
[a.k.a. XP_016880501.1, HPA017258, ENST00000587265.1]
3) '9606.ENSP00000360472':
LGI1 - Leucine-rich glioma-inactivated protein 1; Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors (By similarity). Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway. May play a role in the control of neuroblastoma cell survival.
[a.k.a. EPT, LGI1-221, ENST00000478763]
4) '9606.hsa-miR-6750-5p':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.hsa-miR-7110-3p':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000263388':
NOTCH3 - Neurogenic locus notch homolog protein 3; Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).
[a.k.a. NX_Q9UM47, R-HSA-162582, R-HSA-1912399]
7) '9606.ENSP00000347046':
PDE5A - cGMP-specific 3',5'-cyclic phosphodiesterase; Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide- generated cGMP.
[a.k.a. uc003idf.4, NP_246273.2, PDE5A-204]
8) '9606.ENSP00000220420':
TGM5 - Protein-glutamine gamma-glutamyltransferase 5; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes; Belongs to the transglutaminase superfamily. Transglutaminase family.
[a.k.a. transglutaminase 5, ENSP00000220420, Protein-glutamine gamma-glutamyltransferase 5]
9) '9606.ENSP00000220809':
PLAT - Tissue-type plasminogen activator chain A; Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration; Belongs to the peptidase S1 family.
[a.k.a. 3.4.21.68, BC007231, OMIM:173370]
10) '9606.hsa-miR-6805-5p':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
