Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
payload active
DISEASES
The following proteins in
Homo sapiens
appear to match your input.
Please review the list, then click 'Continue' to proceed.
<- Back
⤓ Mapping
Continue ->
1) '9606.ENSP00000251157':
DOCK7 - Dedicator of cytokinesis protein 7; Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization. As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton. Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells [...]
[a.k.a. Q96N67, R-HSA-6806834, DQ341187]
2) '9606.MT-TL1':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
3) '9606.ENSP00000373706':
DIAPH1 - Protein diaphanous homolog 1; Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers (By similarity). Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization (By similarity). Required for cytokinesis, and transcriptional activation of the serum response factor (By similarity). DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity). Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules [...]
[a.k.a. XM_024454385.1, H7C2W8, DIAPH1-201]
4) '9606.ENSP00000361993':
TIMM8A - Mitochondrial import inner membrane translocase subunit Tim8 A; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8- TIMM13 complex mediates the import of proteins [...]
[a.k.a. AAH70284.1, NP_001139423, OMIM:300356]
5) '9606.ENSP00000399376':
PRNP - Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase deg [...]
[a.k.a. Q96E70, NP_898902, Q27H91]
6) '9606.ENSP00000399851':
POLG - DNA polymerase subunit gamma-1; Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA; Belongs to the DNA polymerase type-A family.
[a.k.a. CAA66719.1, POLG-202, HQ205394]
7) '9606.ENSP00000215570':
TIMM13 - Mitochondrial import inner membrane translocase subunit Tim13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8- TIMM13 complex mediates the import of proteins [...]
[a.k.a. 26517, CCDS12089.1, UPI000012D06F]
8) '9606.ENSP00000312458':
ARV1 - Protein ARV1; Plays a role as a mediator in the endoplasmic reticulum (ER) cholesterol and bile acid homeostasis. Participates in sterol transport out of the ER and distribution into plasma membranes. Belongs to the ARV1 family.
[a.k.a. UPI0000458AFD, BC016309, ENST00000330396]
9) '9606.ENSP00000216471':
SAMD15 - Sterile alpha motif domain containing 15.
[a.k.a. UPI00021CF2A9, SAM15_HUMAN, ENSP00000216471]
10) '9606.ENSP00000348145':
C14orf178 - Uncharacterized protein C14orf178; Chromosome 14 open reading frame 178.
[a.k.a. ENSP00000407405, CCDS9868.1, C14orf178-205]