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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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1) '9606.ENSP00000255030':
CRP - C-reactive protein(1-205); Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.
[a.k.a. R-HSA-173623, CCDS30911, CRP-207]
2) '9606.ENSP00000448580':
SPIC - Transcription factor Spi-C; Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity); Belongs to the ETS family.
[a.k.a. Q8N5J4, ENST00000299272, BC032317]
3) '9606.ENSP00000303507':
BCR - Breakpoint cluster region protein; Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein (GAP) domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound t [...]
[a.k.a. ENST00000292697, AB209991, D22S11]
4) '9606.ENSP00000370588':
CD99 - CD99 antigen; Involved in T-cell adhesion processes and in spontaneous rosette formation with erythrocytes. Plays a role in a late step of leukocyte extravasation helping leukocytes to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1. Involved in T-cell adhesion processes (By similarity).
[a.k.a. ENSP00000405544, R-HSA-202733, NM_001321367.1]
5) '9606.ENSP00000237264':
TBPL1 - TATA box-binding protein-like protein 1; Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box.
[a.k.a. XM_024446592, TBPL1-207, ENST00000367873]
6) '9606.ENSP00000444052':
CES4A - Carboxylesterase 4A; Probable carboxylesterase.
[a.k.a. ENST00000299681, ENST00000567587, BAF85750.1]
7) '9606.ENSP00000501277':
LDB1 - LIM domain-binding protein 1; Binds to the LIM domain of a wide variety of LIM domain- containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity). Belongs to the LDB family.
[a.k.a. AF064491, CLIM2, Q1EQX1]
8) '9606.ENSP00000368104':
BMP2 - Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 ; Belongs to the TGF-beta family.
[a.k.a. R-HSA-2129379, 6OMN, 1REU]
9) '9606.GRTP1-AS1':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000480322':
CD99L2 - CD99 antigen-like protein 2; Plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. Acts at the same site as, but independently of, PECAM1 (By similarity). Homophilic adhesion molecule, but these interactions may not be required for cell aggregation (By similarity); Belongs to the CD99 family.
[a.k.a. NM_001242614.1, R-HSA-202733, UNQ1964/PRO4486]
