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DISEASES
The following proteins in
Homo sapiens
appear to match your input.
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⤓ Mapping
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1) '9606.ENSP00000410294':
FGFR2 - Fibroblast growth factor receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell p [...]
[a.k.a. NP_001138390, FGFR2-208, R-HSA-9006925]
2) '9606.ENSP00000339824':
FGFR3 - Fibroblast growth factor receptor 3; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the inner ear. Ph [...]
[a.k.a. ENSG00000068078, NP_001156685.1, R-HSA-9006925]
3) '9606.LINC01163':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
4) '9606.ENSP00000357811':
TEX36 - Testis-expressed protein 36; Testis expressed 36.
[a.k.a. ENST00000368821, ENST00000526819.5, ENST00000526819]
5) '9606.ENSP00000385361':
VPREB1 - Immunoglobulin iota chain; Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates Ig gene rearrangements in the early steps of B- cell differentiation.
[a.k.a. R-HSA-202733, 7441, ENST00000403807]
6) '9606.ENSP00000204961':
EFNB1 - Ephrin-B1 intracellular domain; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binding to Eph receptors residing on adjacent cells leads to contact-dependent bidirectional signaling into neighboring cells. Shows high affinity for the receptor tyrosine kinase EPHB1/ELK. Can also bind EPHB2 and EPHB3. Binds to, and induces collapse of, commissural axons/growth cones in vitro (By similarity). May play a role in constraining the orientati [...]
[a.k.a. Ephrin-B1, LERK-2, NP_004420]
7) '9606.ENSP00000239243':
MSX2 - Homeobox protein MSX-2; Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter; Belongs to the Msh homeobox family.
[a.k.a. AAD14169.1, BAA13949.1, ENST00000239243]
8) '9606.ENSP00000224652':
ATE1 - Arginyl-tRNA--protein transferase 1; Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues (By similarity).
[a.k.a. NM_001001976, XP_016871089, NM_001288734.1]
9) '9606.ENSP00000396622':
MROH7 - Maestro heat like repeat family member 7.
[a.k.a. AL832492, ENSP00000399703, UPI000198C4E3]
10) '9606.ENSP00000447241':
FRS2 - Fibroblast growth factor receptor substrate 2; Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
[a.k.a. NM_001278357, ENSP00000381083, ENST00000551325.1]
