Disease-gene associations mined from literature

DPYSL2 disease associations

DPYSL2 [ENSP00000309539]

Collapsin response mediator protein 2; Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis; Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

Synonyms:  DPYSL2,  DPYSL2p,  hDPYSL2,  A9CQZ2,  DPYSL2-001 ...

Linkouts:  STRING  Pharos  UniProt  OMIM