BCL2L1 disease associations
Apoptosis regulator Bcl-X; Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis; Belongs to the Bcl-2 family.
Synonyms: BCL2L1, BCL2L1p, hBCL2L1, Q07817, Q5QP56 ...