DISEASES

Disease-gene associations mined from literature

ADD2 disease associations

ADD2 [ENSP00000264436]

Erythrocyte adducin subunit beta; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit; Belongs to the aldolase class II family. Adducin subfamily.

Synonyms:  ADD2,  ADD2p,  hADD2,  ADD2-001,  ADD2-002 ...

Linkouts:  STRING  Pharos  UniProt  OMIM