ADD2 disease associations
Erythrocyte adducin subunit beta; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit; Belongs to the aldolase class II family. Adducin subfamily.
Synonyms: ADD2, ADD2p, hADD2, ADD2-001, ADD2-002 ...