DISEASES

Disease-gene associations mined from literature

Human genes for breast large cell neuroendocrine carcinoma

Breast large cell neuroendocrine carcinoma [DOID:6657]

A breast carcinoma that is characterized by large cell size, polygonal shape, low nuclear-cytoplasmic ratio, finely granular eosinophilic cytoplasm, occasionally prominent nucleoli, peripheral palisading, mitosis, and necrosis and in which greater than 50% of the tumor cells are positive for neuroendocrine markers (NSE, chromogranin A, synaptophysin).

Synonyms:  breast large cell neuroendocrine carcinoma,  DOID:6657,  breast large cell neuroendocrine carcinomas