DISEASES

Disease-gene associations mined from literature

JensenLab

Human genes for autosomal recessive distal hereditary motor neuronopathy 1

Autosomal recessive distal hereditary motor neuronopathy 1 [DOID:0111064]

A spinal muscular atrophy characterized by autosomal recessive inheritance of severe respiratory distress resulting from diaphragmatic paralysis that predominantly involves the upper limbs and distal muscles that has_material_basis_in homozygous or compound heterozygous mutation in the IGHMBP2 gene on chromosome 11q13.

Synonyms:  autosomal recessive distal hereditary motor neuronopathy 1,  DOID:0111064,  autosomal recessive distal familial motor neuronopathy 1,  DSMA1,  SIANRF ...