DISEASES

Disease-gene associations mined from literature

SearchDownloadsAbout

Human genes for leukocyte adhesion deficiency 3

Leukocyte adhesion deficiency 3 [DOID:0110912]

A leukocyte adhesion deficiency that is characterized by a defect in beta integrins 1, 2, and 3; which impairs the integrin activation cascade and has_material_basis_in mutation in FERMT3 gene on chromosome 11q12.

Synonyms:  leukocyte adhesion deficiency 3,  DOID:0110912,  IADD,  LAD1 variant,  LAD1V ...

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.