DISEASES

Disease-gene associations mined from literature

Human genes for leukocyte adhesion deficiency 3

Leukocyte adhesion deficiency 3 [DOID:0110912]

A leukocyte adhesion deficiency that is characterized by a defect in beta integrins 1, 2, and 3; which impairs the integrin activation cascade and has_material_basis_in mutation in FERMT3 gene on chromosome 11q12.

Synonyms:  leukocyte adhesion deficiency 3,  DOID:0110912,  IADD,  LAD1 variant,  LAD1V ...