DISEASES

Disease-gene associations mined from literature

Human genes for hereditary spastic paraplegia 4

Hereditary spastic paraplegia 4 [DOID:0110792]

A hereditary spastic paraplegia that is characterized by slowly progressive muscle weakness and spasticity and has_material_basis_in mutation in the SPAST gene on chromosome 2p22.

Synonyms:  hereditary spastic paraplegia 4,  DOID:0110792,  familial spastic paraplegia 4,  SPG4,  autosomal dominant spastic paraplegia 4 ...