Disease-gene associations mined from literature

Human genes for multiple endocrine neoplasia type 4

Multiple endocrine neoplasia type 4 [DOID:0080137]

A multiple endocrine neoplasia that is characterized by hyperparathyroidism and multiple endocrine tumors and that has_material_basis_in mutations in the CDKN1B gene on chromosome 12p13 resulting in a reduction in the amount of functional p27 tumor suppressor protein which allows cells to grow and divide unchecked.

Synonyms:  multiple endocrine neoplasia type 4,  DOID:0080137,  Multiple Endocrine Neoplasia, Type IV,  Multiple Endocrine Neoplasia Type IV,  Type IV Multiple Endocrine Neoplasia ...