Human genes for immunodeficiency with hyper-IgM type 4
Immunodeficiency with hyper-IgM type 4 [DOID:0060760]
A hyper IgM syndrome that is characterized by normal or increased serum IgM concentrations associated with low or absent serum IgG, IgA, and IgE concentrations, indicating a defect in the class-switch recombination (CSR) process.
Synonyms: immunodeficiency with hyper-IgM type 4, DOID:0060760, immunodeficiency with hyperIgM type 4, HIGM4, hyper-IgM syndrome type 4 ...