DISEASES

Disease-gene associations mined from literature

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Human genes for thrombophilia due to activated protein C resistance

Thrombophilia due to activated protein C resistance [DOID:0111902]

A thrombophilia characterized by resistance of F5 to cleavage and inactivation and increased tendency for thrombosis that has_material_basis_in heterozygous mutation in F5 on chromosome 1q24.2.

Synonyms:  thrombophilia due to activated protein C resistance,  DOID:0111902,  thrombophilia due to activated protein C resistances,  activated protein C resistance,  APC resistance ...

The disease-gene associations are derived from automatic text mining of the biomedical literature, manually curated database annotations, cancer mutation data, and genome-wide association studies. The confidence of each association is signified by stars, where ★★★★★ is the highest confidence and ★☆☆☆☆ is the lowest.

Developed by Sune Frankild, Alexander Junge, Albert Pallejà, Dhouha Grissa, Kalliopi Tsafou, and Lars Juhl Jensen from the Novo Nordisk Foundation Center for Protein Research.