DISEASES

Disease-gene associations mined from literature

Literature on WSB1

WSB1 [ENSP00000262394]

WD repeat and SOCS box-containing protein 1; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation; WD repeat domain containing

Synonyms:  WSB1,  WSB1p,  hWSB1,  A0A024QZ36,  A0A024QZ51 ...

Linkouts:  STRING  Pharos  UniProt  OMIM