DISEASES

Disease-gene associations mined from literature

Literature on NUBP1

NUBP1 [ENSP00000283027]

Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity).

Synonyms:  NUBP1,  NUBP1p,  hNUBP1,  I3L531,  NUBP1-001 ...

Linkouts:  STRING  Pharos