Literature on CASP7
Caspase 7, apoptosis-related cysteine peptidase; Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly- 217' bond. Overexpression promotes programmed cell death.
Synonyms: CASP7, CASP7p, hCASP7, P55210, Q5SVL2 ...