Literature on VTCN1
V-set domain containing T cell activation inhibitor 1; Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation; Immunoglobulin like domain containing
Synonyms: VTCN1, VTCN1p, hVTCN1, Q5T2L0, Q7Z7D3 ...