DISEASES

Disease-gene associations mined from literature

Literature on PAPPA2

PAPPA2 [ENSP00000356634]

Pregnancy-associated plasma protein A2; Metalloproteinase which specifically cleaves insulin- like growth factor binding protein (IGFBP)-5 at the '163-Ser-|- Lys-164' bond. Shows limited proteolysis toward IGFBP-3; Belongs to the peptidase M43B family.

Synonyms:  PAPPA2,  PAPPA2p,  hPAPPA2,  Q9BXP8,  PLAC3 ...

Linkouts:  STRING  Pharos  UniProt