DISEASES

Disease-gene associations mined from literature

Literature on ARHGEF16

ARHGEF16 [ENSP00000367629]

Rho guanine nucleotide exchange factor (GEF) 16; Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6; Pleckstrin homology domain containing

Synonyms:  ARHGEF16,  B0QZD3,  B0QZD4,  Q5VV41,  B0QZD3p ...

Linkouts:  STRING  Pharos  UniProt