DISEASES

Disease-gene associations mined from literature

Literature on ACACB

ACACB [ENSP00000341044]

acetyl-CoA carboxylase beta; Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in inhibition of fatty acid and glucose oxidation and enhancement of fat storage (By similarity). May play a role in regulation of mitochondrial fatty acid oxidation through malonyl- CoA-dependent inhibition of carnitine palmitoyltransferase 1 (By similarity).

Synonyms:  ACACB,  ACACB-001,  ACACB-002,  ACACB-004,  ACACB-005 ...

Linkouts:  STRING  Pharos  UniProt  OMIM