DISEASES

Disease-gene associations mined from literature

Literature on HTN3

HTN3 [ENSP00000432561]

Basic histidine-rich protein; Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9.

Synonyms:  HTN3,  HTN3p,  hHTN3,  P15516,  X6RAH8 ...

Linkouts:  STRING  Pharos