Literature on SLC5A11
Solute carrier family 5 (sodium/inositol cotransporter), member 11; Involved in the sodium-dependent cotransport of myo- inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D- xylose. May induce apoptosis through the TNF-alpha, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
Synonyms: SLC5A11, SLC5A11p, hSLC5A11, H3BN85, I3L1G0 ...