Literature on RNF114
RING-type E3 ubiquitin transferase RNF114; E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis; Ring finger proteins
Synonyms: RNF114, RNF114p, hRNF114, H0UI65, Q9Y508 ...