Disease-gene associations mined from literature

Literature on IZUMO1

IZUMO1 [ENSP00000327786]

Izumo sperm-egg fusion protein 1; Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'.

Synonyms:  IZUMO1,  IZUMO1p,  hIZUMO1,  Q8IYV9,  Q8IYV9p ...

Linkouts:  STRING  Pharos