DISEASES

Disease-gene associations mined from literature

Literature on HAS1

HAS1 [ENSP00000222115]

Hyaluronic acid synthase 1; Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito- oligosaccharide depending on the substrate (By similarity); Glycosyltransferase family 2

Synonyms:  HAS1,  HAS1p,  hHAS1,  D2N2G5,  G3V1S7 ...

Linkouts:  STRING  Pharos  UniProt  OMIM