DISEASES

Disease-gene associations mined from literature

Literature on PSD4

PSD4 [ENSP00000245796]

Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B; Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5- bisphosphate and phosphatidylinositol 4,5-bisphosphate; Pleckstrin homology domain containing

Synonyms:  PSD4,  PSD4p,  hPSD4,  A0A024R521,  B3KN27 ...

Linkouts:  STRING  Pharos  UniProt  OMIM