DISEASES

Disease-gene associations mined from literature

Literature on MON1A

MON1A [ENSP00000296473]

MON1 secretory trafficking family member A; Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form.

Synonyms:  MON1A,  MON1Ap,  hMON1A,  Q86VX9,  X6R3V9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM