DISEASES

Disease-gene associations mined from literature

Literature on C2

C2 [ENSP00000299367]

Complement component 2; Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase; Belongs to the peptidase S1 family.

Synonyms:  C2p,  hC2,  B3KTX9,  C9JYQ5,  E9PDZ0 ...

Linkouts:  STRING  Pharos