DISEASES

Disease-gene associations mined from literature

Literature on PTPRK

PTPRK [ENSP00000357196]

Receptor-type tyrosine-protein phosphatase kappa; Regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Negative regulator of EGFR signaling pathway. Forms complexes with beta-catenin and gamma-catenin/plakoglobin. Beta-catenin may be a substrate for the catalytic activity of PTPRK/PTP-kappa; Fibronectin type III domain containing

Synonyms:  PTPRK,  E9PGC5,  E9PMV4,  E9PRW2,  H0Y6V4 ...

Linkouts:  STRING  Pharos  UniProt  OMIM