DISEASES

Disease-gene associations mined from literature

Literature on ADCY10

ADCY10 [ENSP00000356825]

Testicular soluble adenylyl cyclase; Catalyzes the formation of the signaling molecule cAMP. May function as sensor that mediates responses to changes in cellular bicarbonate and CO(2) levels. Has a critical role in mammalian spermatogenesis by producing the cAMP which regulates cAMP-responsive nuclear factors indispensable for sperm maturation in the epididymis. Induces capacitation, the maturational process that sperm undergo prior to fertilization (By similarity). Involved in ciliary beat regulation; Adenylate cyclases

Synonyms:  ADCY10,  ADCY10p,  hADCY10,  Q96PN6,  U3KPS9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM