Disease-gene associations mined from literature

Literature on JDP2

JDP2 [ENSP00000267569]

Jun dimerization protein 2; Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin; Basic leucine zipper proteins

Synonyms:  JDP2,  JDP2p,  hJDP2,  A0A024R6D7,  H0YKE4 ...

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