DISEASES

Disease-gene associations mined from literature

Literature on TTF1

TTF1 [ENSP00000333920]

Transcription termination factor, RNA polymerase I; Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity; Myb/SANT domain containing

Synonyms:  TTF1,  LOC102725085,  TTF1p,  hTTF1,  A0A024R8C1 ...

Linkouts:  STRING  Pharos  UniProt  OMIM