DISEASES

Disease-gene associations mined from literature

Literature on SCARB1

SCARB1 [ENSP00000261693]

Collagen type I receptor, thrombospondin receptor-like 1; Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux. Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity; Scavenger receptors

Synonyms:  SCARB1,  SCARB1p,  hSCARB1,  A0A024RBS4,  B7ZKQ9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM