DISEASES

Disease-gene associations mined from literature

Literature on MED10

MED10 [ENSP00000255764]

Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Synonyms:  MED10,  MED10p,  hMED10,  Q9BTT4,  Q9BTT4p ...

Linkouts:  STRING  Pharos  UniProt  OMIM