DISEASES

Disease-gene associations mined from literature

Literature on KIF26B

KIF26B [ENSP00000385545]

Kinesin-like protein KIF26B; Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF26 subfamily.

Synonyms:  KIF26B,  KIF26Bp,  hKIF26B,  B4DF75,  B7WPD9 ...

Linkouts:  STRING  Pharos  UniProt  OMIM