DISEASES

Disease-gene associations mined from literature

Literature on HMGCLL1

HMGCLL1 [ENSP00000381654]

Endoplasmic reticulum 3-hydroxymethyl-3-methylglutaryl-CoA lyase; Non-mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy- 3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis, the products of which support energy production in nonhepatic animal tissues.

Synonyms:  HMGCLL1,  HMGCLL1p,  hHMGCLL1,  B7Z212,  B7Z4D4 ...

Linkouts:  STRING  Pharos  UniProt