DISEASES

Disease-gene associations mined from literature

Literature on LILRB2

LILRB2 [ENSP00000375629]

Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2; Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Synonyms:  LILRB2,  LILRB2p,  hLILRB2,  A2IXV5,  Q8N423 ...

Linkouts:  STRING  Pharos