Disease-gene associations mined from literature

Literature on PTCHD4

PTCHD4 [ENSP00000341914]

Patched domain-containing protein 4; Could act as a repressor of canonical hedgehog signaling by antagonizing the effects of SMO, as suggested by down- regulation of hedgehog target genes, including GLI1, PTCH1, and PTCH2 in PTCHD4-expressing cells; Belongs to the patched family.

Synonyms:  PTCHD4,  PTCHD4p,  hPTCHD4,  B0QZ29,  B2RPC0 ...

Linkouts:  STRING  Pharos  UniProt