DISEASES

Disease-gene associations mined from literature

Literature on GRK1

GRK1 [ENSP00000334876]

G protein-coupled receptor kinase 1; Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

Synonyms:  GRK1,  GRK1p,  hGRK1,  Q15835,  Q71VB6 ...

Linkouts:  STRING  Pharos  UniProt  OMIM