Disease-gene associations mined from literature

Literature on REC114

REC114 [ENSP00000328423]

Meiotic recombination protein REC114; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with IHO1/CCDC36 and MEI4, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis.

Synonyms:  REC114,  REC114p,  hREC114,  H0YKR2,  Q7Z4M0 ...

Linkouts:  STRING  Pharos  UniProt