Literature on ALX1
Cartilage homeoprotein 1; Sequence-specific DNA-binding transcription factor that binds palindromic sequences within promoters and may activate or repress the transcription of a subset of genes. Most probably regulates the expression of genes involved in the development of mesenchyme-derived craniofacial structures. Early on in development, it plays a role in forebrain mesenchyme survival. May also induce epithelial to mesenchymal transition (EMT) through the expression of SNAI1; Belongs to the paired homeobox family.
Synonyms: ALX1, ALX1p, hALX1, HEL23, Q15699 ...