DISEASES

Disease-gene associations mined from literature

Literature on HMGN1

HMGN1 [ENSP00000370125]

High mobility group nucleosome-binding domain-containing protein 1; Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. Inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2 (By similarity); Belongs to the HMGN family.

Synonyms:  HMGN1,  HMGN1p,  hHMGN1,  LOC101927733,  A6NEL0 ...

Linkouts:  STRING  Pharos  UniProt  OMIM