DISEASES

Disease-gene associations mined from literature

Literature on LPHN1

LPHN1 [ENSP00000340688]

Calcium-independent alpha-latrotoxin receptor 1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity).

Synonyms:  LPHN1,  LPHN1p,  hLPHN1,  ADGRL1,  K7ESH3 ...

Linkouts:  STRING  Pharos  UniProt